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A developmental condensin I complex assists the <i>Paramecium</i> PiggyMac domesticated transposase during programmed DNA elimination

2025-10-03

Abstract excerpt

Prokaryotes and eukaryotes use diverse strategies to cope with invading mobile genetic elements, including programmed DNA elimination (PDE). In the ciliate Paramecium , elimination of transposable elements and their relics requires the PiggyMac (Pgm) endonuclease and its five PgmL partners, yet how this machinery is targeted to cleavage sites remains unclear. Here, we identified condensin I subunits in the proxim...

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Literature Corpus work
ad836dad-698b-5ceb-a639-0147c211a088
DOI
10.1101/2025.10.03.680307
Open publication

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A developmental condensin I complex assists the <i>Paramecium</i> PiggyMac domesticated transposase during programmed DNA eliminationDOI 10.1101/2025.10.03.680307
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