Back to search

Article

The tiny germline chromosomes of Paramecium aurelia have an exceptionally high recombination rate and are capped by a new class of Helitrons

2025-11-07

Abstract excerpt

<h4>Background: </h4> Paramecia belong to the ciliate phylum of unicellular eukaryotes characterized by nuclear dimorphism. A diploid germline micronucleus (MIC) transmits genetic information across sexual generations. A polyploid transcriptionally active somatic macronucleus (MAC) develops at each sexual generation from a copy of the MIC through programmed DNA elimination (PDE) of > 30% of germline DNA. PDE requi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e4a9b789-aa62-5767-bd46-12dbff9135ec
DOI
10.1101/2025.11.06.686955
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The tiny germline chromosomes of Paramecium aurelia have an exceptionally high recombination rate and are capped by a new class of HelitronsDOI 10.1101/2025.11.06.686955
Massive colonization of protein-coding exons by selfish genetic elements in <i>Paramecium</i> germline genomesSemantic proximity
Inter-generational nuclear crosstalk links the control of gene expression to programmed genome rearrangements during the <i>Paramecium</i> sexual cycleSemantic proximity
Developmental timing of programmed DNA elimination in <i>Paramecium tetraurelia</i> recapitulates germline transposon evolutionary dynamicsSemantic proximity
Germline-limited transposon remnants foster somatic genome diversificationSemantic proximity
Germline-limited transposon remnants foster somatic genome diversificationSemantic proximity
Analysis of sequence variability in the macronuclear DNA of Paramecium tetraurelia: a somatic view of the germline.Semantic proximity
Remembrance of things past retrieved from the Paramecium genome.Semantic proximity
N6-methyldeoxyadenosine is a transgenerational epigenetic mark protecting DNA from deletionSemantic proximity
Identification and analysis of functional associations among natural eukaryotic genome editing componentsSemantic proximity
N6-methyldeoxyadenosine is a transgenerational epigenetic mark protecting DNA from deletionSemantic proximity
Two paralogous PHD finger proteins participate in <i>Paramecium tetraurelia</i> ’s natural genome editingSemantic proximity
Nuclear dualism without extensive DNA elimination in the ciliate <i>Loxodes magnus</i>Semantic proximity
Select a neighboring publication to make it the new centre.