Article
Genetic regulation of atherosclerotic plaque size and morphology in the innominate artery of hyperlipidemic mice.
Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2009
Bennett Brian J, Wang Susanna S, Wang Xuping, Wu Xiaohui, Lusis Aldons J
Abstract excerpt
OBJECTIVE: We sought to determine the genetic factors contributing to atherosclerotic plaque size and cellular composition in the innominate artery, a murine model of advanced atherosclerosis. METHODS AND RESULTS: We examined genetic contributions to innominate atherosclerotic plaque size and cellular composition in an intercross between C57BL/6J.Apoe(-/-), a strain susceptible to aortic lesions, and...
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