Article
Genetic analysis of atherosclerosis and glucose homeostasis in an intercross between C57BL/6 and BALB/cJ apolipoprotein E-deficient mice.
Circulation. Cardiovascular genetics - 1 Apr 2012
Zhang Zhimin, Rowlan Jessica S, Wang Qian, Shi Weibin
Abstract excerpt
BACKGROUND: Diabetic patients have an increased risk of developing atherosclerosis and related complications compared with nondiabetic individuals. The increased cardiovascular risk associated with diabetes is due in part to genetic variations that influence both glucose homeostasis and atherosclerotic lesion growth. Mouse strains C57BL/6J (B6) and BALB/cJ (BALB) exhibit distinct differences in fasting plasma...
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