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Article

Mannose-binding lectin and l-ficolin polymorphisms in patients with community-acquired pneumonia caused by intracellular pathogens.

Immunology - 1 May 2017

van Kempen Gijs, Meijvis Sabine, Endeman Henrik, Vlaminckx Bart, Meek Bob, de Jong Ben, Rijkers Ger, Bos Willem Jan

Abstract excerpt

Community-acquired pneumonia (CAP) is the leading infectious disease requiring hospitalization in the western world. Genetic variability affecting the host response to infection may play a role in susceptibility and outcome in patients with CAP. Mannose-binding lectin (MBL) and l-ficolin (l-FCN) are two important activators of the complement system and they can enhance phagocytosis by opsonization. In a...

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Source

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Identifiers

PMID: 28032346
DOI: 10.1111/imm.12705
PMCID: PMC5382344

Genes

FCN2
MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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