Article
Mannose-binding lectin genotypes in susceptibility to community-acquired pneumonia.
Chest - 1 Dec 2008
Endeman Henrik, Herpers Bjorn L, de Jong Ben A W, Voorn G Paul, Grutters Jan C, van Velzen-Blad Heleen, Biesma Douwe H
Abstract excerpt
BACKGROUND: Community-acquired pneumonia (CAP) is most frequently caused by Streptococcus pneumoniae, Haemophilus influenzae, atypical pathogens, and respiratory viruses. Susceptibility to CAP can be increased by single-nucleotide polymorphisms (SNPs) within the mannose-binding lectin (MBL) gene. We questioned whether MBL polymorphisms are associated with the susceptibility to and outcome of CAP and its most...
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