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Article

Acute-phase responsiveness of mannose-binding lectin in community-acquired pneumonia is highly dependent upon MBL2 genotypes.

Clinical and experimental immunology - 1 Jun 2009

Herpers B L, Endeman H, de Jong B A W, de Jongh B M, Grutters J C, Biesma D H, van Velzen-Blad H

Abstract excerpt

Mannose-binding lectin (MBL) is a pattern recognition receptor of the complement system and plays an important role in innate immunity. Whether or not MBL acts as an acute-phase response protein in infection has been an issue of extensive debate, because MBL responses have shown a high degree of heterogeneity. Single nucleotide polymorphisms (SNPs) in the promoter (wild-type Y versus X) and exon 1 (A versus 0) of...

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Identifiers

PMID: 19438602
DOI: 10.1111/j.1365-2249.2009.03929.x
PMCID: PMC2691978

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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