Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Acute-phase responsiveness of mannose-binding lectin in community-acquired pneumonia is highly dependent upon MBL2 genotypes.

Clinical and experimental immunology - 1 Jun 2009

Herpers B L, Endeman H, de Jong B A W, de Jongh B M, Grutters J C, Biesma D H, van Velzen-Blad H

Abstract excerpt

Mannose-binding lectin (MBL) is a pattern recognition receptor of the complement system and plays an important role in innate immunity. Whether or not MBL acts as an acute-phase response protein in infection has been an issue of extensive debate, because MBL responses have shown a high degree of heterogeneity. Single nucleotide polymorphisms (SNPs) in the promoter (wild-type Y versus X) and exon 1 (A versus 0) of...

Topics

Acute Disease
Acute-Phase Reaction
Adult
Aged
Aged, 80 and over
C-Reactive Protein
Community-Acquired Infections
Female
Genotype
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mannose-Binding Lectin

Middle Aged

Pneumonia

Prospective Studies

Source

Open in PubMed Open full text

Identifiers

PMID: 19438602
DOI: 10.1111/j.1365-2249.2009.03929.x
PMCID: PMC2691978

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Acute-phase responsiveness of mannose-binding lectin in community-acquired pneumonia is highly dependent upon MBL2 genotypes.PMID 19438602Read ↗

Mannose-binding lectin and mannose-binding lectin-associated serine protease 2 in susceptibility, severity, and outcome of pneumonia in adults.Semantic proximity Read ↗

The MBL2 genotype relates to COVID-19 severity and may help to select the optimal therapy.Semantic proximity Read ↗

Mannose-binding lectin genotypes in susceptibility to community-acquired pneumonia.Semantic proximity Read ↗

Mannose-binding lectin does not act as an acute-phase reactant in adults with community-acquired pneumococcal pneumonia.Semantic proximity Read ↗

Mannan-binding lectin deficiency - Good news, bad news, doesn't matter?Semantic proximity Read ↗

Mannose binding lectin acute phase activity in patients with severe infection.Semantic proximity Read ↗

Impact of mannose-binding lectin on susceptibility to infectious diseases.Semantic proximity Read ↗

Low serum mannose-binding lectin level increases the risk of death due to pneumococcal infection.Semantic proximity Read ↗

Association between mannose binding lectin gene polymorphisms and clinical severity of COVID-19 in children.Semantic proximity Read ↗

Mannose-binding lectin and l-ficolin polymorphisms in patients with community-acquired pneumonia caused by intracellular pathogens.Semantic proximity Read ↗

The role of mannose-binding lectin in pneumococcal infection.Semantic proximity Read ↗

Genotypes coding for low serum levels of mannose-binding lectin are underrepresented among individuals suffering from noninfectious systemic inflammatory response syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.