Article
Genetics of community-acquired pneumonia.
Seminars in respiratory and critical care medicine - 1 Dec 2005
Wunderink Richard G, Waterer Grant W
Abstract excerpt
The variable clinical presentation of community-acquired pneumonia (CAP) suggests a genetic predisposition. Specific mutations or polymorphisms in host response genes such as pattern recognition molecules (PRMs), inflammatory molecules, and the coagulation system are likely to play a role in this variable response to CAP. Mannose-binding lectin polymorphisms appear to play a more dominant role in CAP than other...
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