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Article

Deficiency of γδT cells protects against abdominal aortic aneurysms by regulating phosphoinositide 3-kinase/AKT signaling.

Journal of vascular surgery - 1 Mar 2018

Zhang Shuai, Kan Xiaoyu, Li Yulin, Li Ping, Zhang Congcong, Li Guang, Du Jie, You Bin

Abstract excerpt

OBJECTIVE: It is known that T lymphocytes are activated in human abdominal aortic aneurysms (AAAs). γδT cells, as a subset of T cells, play a role in many inflammation-related diseases. However, whether γδT cells participate in the formation of AAA remains unknown. In this study, we explored the role of γδT cells in AAA lesions. METHODS AND RESULTS: Using the porcine pancreatic elastase-induced AAA model, we...

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Share to Aorta, Abdominal
Share to Aortic Aneurysm, Abdominal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apoptosis Regulatory Proteins

Share to Dilatation, Pathologic

Share to Pancreatic Elastase

Share to Phosphatidylinositol 3-Kinase

Share to Receptors, Antigen, T-Cell, gamma-delta

Share to Vascular Remodeling

Source

Identifiers

PMID: 28024851
DOI: 10.1016/j.jvs.2016.03.474

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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