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Article

Inhibition of STING pathway attenuates experimental abdominal aortic aneurysm progression.

Acta pharmacologica Sinica - 1 Jun 2026

Chen Yu-Xin, Shen Chen-Rui, Xu Fang-Fang, Han Chen-Jun, Xi Yu-Jie, Shi Yu, Xu Yu-Ping, Li Dong-Jie, Zhou Jian, Shen Fu-Ming, Fu Hui

Abstract excerpt

Abdominal aortic aneurysm (AAA) is a chronic, inflammatory and degenerative vascular disease. Previous studies have demonstrated that stimulator of interferon genes (STING) is involved in multiple inflammatory diseases. However, the role of STING in AAA formation and its possible mechanisms have yet to be investigated. Here, we investigated the role of STING in the development of AAA using two murine AAA models...

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Share to Angiotensin II
Share to Aortic Aneurysm, Abdominal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41667721
DOI: 10.1038/s41401-026-01758-0
PMCID: PMC13197471

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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