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Article

Aorta Regulatory T Cells with a Tissue-Specific Phenotype and Function Promote Tissue Repair through Tff1 in Abdominal Aortic Aneurysms.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) - 1 Mar 2022

Li Jingyong, Xia Ni, Li Dan, Wen Shuang, Qian Shirui, Lu Yuzhi, Gu Muyang, Tang Tingting, Jiao Jiao, Lv Bingjie, Nie Shaofang, Hu Desheng, Liao Yuhua, Yang Xiangping, Shi Guoping, Cheng Xiang

Abstract excerpt

In addition to maintaining immune tolerance, Foxp3+ regulatory T cells (Tregs) perform specialized functions in tissue homeostasis and remodeling. However, whether Tregs in aortic aneurysms have a tissue-specific phenotype and function is unclear. Here, a special group of Tregs that potentially inhibit abdominal aortic aneurysm (AAA) progression are identified and functionally characterized. Aortic Tregs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35332699
DOI: 10.1002/advs.202104338
PMCID: PMC8948580

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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