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Deciphering abdominal aortic diseases through T-cell clonal repertoire of perivascular adipose tissue

2023-12-07

Abstract excerpt

Recent studies suggested that immune-mediated inflammation of perivascular adipose tissue (PVAT) of abdominal aortic aneurysms (AAA) contributes to disease development and progression. Whether the PVAT of AAA is characterized by a specific adaptive immune signature remains unknown. To investigate this hypothesis, we sequenced the T-cell receptor β-chain (TCRβ) in the PVAT of AAA patients and compared with patients...

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Literature Corpus work
5f3f00bf-ee88-5bd3-a3bc-d3496365e81a
DOI
10.1101/2023.12.05.570098
Open publication

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Deciphering abdominal aortic diseases through T-cell clonal repertoire of perivascular adipose tissueDOI 10.1101/2023.12.05.570098
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