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Article

The Clinicopathological Significance of Epigenetic Silencing of VHL Promoter and Renal Cell Carcinoma: A Meta-Analysis

1 Jan 2016

Abstract excerpt

BACKGROUND/AIMS: Von Hippel-Lindau gene (VHL) has been reported as a tumor-suppressor gene in some cancers. However, the association between VHL promoter hypermethylation and renal cell carcinoma (RCC) remains to be clarified. We are the first to systematically integrate published papers to assess the role of hypermethylated VHL in RCC. METHODS: The potential relevant papers were searched via PubMed, Embase,...

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PMID: 27997886
DOI: 10.1159/000453198

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