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Article

Unique molecular alteration patterns in von Hippel-Lindau (VHL) gene in a cohort of sporadic renal cell carcinoma patients from Pakistan.

Mutation research - 1 Jan 2000

Khaliq Shagufta, Ajaz Sadia, Firasat Sadaf, Shahid Saba, Hasan Asad Shahzad, Sultan Gauhar, Mohsin Rehan, Hashmi Altaf, Mubarak Muhammed, Naqvi Syed Ali Anwar, Rizvi Syed Adib-Ul-Hasan, Mehdi Syed Qasim, Abid Aiysha

Abstract excerpt

BACKGROUND: Renal cell carcinoma (RCC) is the most frequent form of kidney cancer in adults. Somatic mutations that inactivate the von Hippel-Lindau (VHL) gene are the most common cause of RCC. The frequencies of molecular changes in the VHL gene in RCCs vary among different populations. So far, a single chromosomal-based study has been reported from a South Asian population. This report presents, for the first...

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Source

Identifiers

PMID: 24727139
DOI: 10.1016/j.mrfmmm.2014.03.008

Genes

VHL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Unique molecular alteration patterns in von Hippel-Lindau (VHL) gene in a cohort of sporadic renal cell carcinoma patients from Pakistan.PMID 24727139Read ↗

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