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Article

VHL gene mutations in renal cell carcinoma: role as a biomarker of disease outcome and drug efficacy.

Current oncology reports - 1 Mar 2009

Cowey C Lance, Rathmell W Kimryn

Abstract excerpt

The therapeutic landscape for renal cell carcinoma (RCC) has changed drastically over the past several years with the emergence of molecularly targeted therapies. With previous prognostic and predictive tools based on studies of patients treated with cytokine therapies, confirmation of these prior methods and discovery of new markers in this new era of targeted therapy are of great importance. Alteration of the...

Topics

Biomarkers, Tumor
Carcinoma, Renal Cell
Humans
Kidney Neoplasms
Mutation
Prognosis
Vascular Endothelial Growth Factor A
Von Hippel-Lindau Tumor Suppressor Protein

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 19216840
DOI: 10.1007/s11912-009-0015-5
PMCID: PMC2873025

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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