Article
VHL gene mutations in renal cell carcinoma: role as a biomarker of disease outcome and drug efficacy.
Current oncology reports - 1 Mar 2009
Cowey C Lance, Rathmell W Kimryn
Abstract excerpt
The therapeutic landscape for renal cell carcinoma (RCC) has changed drastically over the past several years with the emergence of molecularly targeted therapies. With previous prognostic and predictive tools based on studies of patients treated with cytokine therapies, confirmation of these prior methods and discovery of new markers in this new era of targeted therapy are of great importance. Alteration of the...
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