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Article

Genome-wide association mapping including phenotypes from relatives without genotypes.

Genetics research - 1 Apr 2012

Wang H, Misztal I, Aguilar I, Legarra A, Muir W M

Abstract excerpt

A common problem for genome-wide association analysis (GWAS) is lack of power for detection of quantitative trait loci (QTLs) and precision for fine mapping. Here, we present a statistical method, termed single-step GBLUP (ssGBLUP), which increases both power and precision without increasing genotyping costs by taking advantage of phenotypes from other related and unrelated subjects. The procedure achieves these...

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Identifiers

PMID: 22624567
DOI: 10.1017/S0016672312000274

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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