Article
PBAP: a pipeline for file processing and quality control of pedigree data with dense genetic markers.
Bioinformatics (Oxford, England) - 1 Dec 2015
Nato Alejandro Q, Chapman Nicola H, Sohi Harkirat K, Nguyen Hiep D, Brkanac Zoran, Wijsman Ellen M
Abstract excerpt
MOTIVATION: Huge genetic datasets with dense marker panels are now common. With the availability of sequence data and recognition of importance of rare variants, smaller studies based on pedigrees are again also common. Pedigree-based samples often start with a dense marker panel, a subset of which may be used for linkage analysis to reduce computational burden and to limit linkage disequilibrium between...
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