Article
Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls.
Human molecular genetics - 15 Jun 2013
Zheng Wei, Zhang Ben, Cai Qiuyin, Sung Hyuna, Michailidou Kyriaki, Shi Jiajun, Choi Ji-Yeob, Long Jirong, Dennis Joe, Humphreys Manjeet K, Wang Qin, Lu Wei, Gao Yu-Tang, Li Chun, Cai Hui, Park Sue K, Yoo Keun-Young, Noh Dong-Young, Han Wonshik, Dunning Alison M, Benitez Javier, Vincent Daniel, Bacot Francois, Tessier Daniel, Kim Sung-Won, Lee Min Hyuk, Lee Jong Won, Lee Jong-Young, Xiang Yong-Bing, Zheng Ying, Wang Wenjin, Ji Bu-Tian, Matsuo Keitaro, Ito Hidemi, Iwata Hiroji, Tanaka Hideo, Wu Anna H, Tseng Chiu-chen, Van Den Berg David, Stram Daniel O, Teo Soo Hwang, Yip Cheng Har, Kang In Nee, Wong Tien Y, Shen Chen-Yang, Yu Jyh-Cherng, Huang Chiun-Sheng, Hou Ming-Feng, Hartman Mikael, Miao Hui, Lee Soo Chin, Putti Thomas Choudary, Muir Kenneth, Lophatananon Artitaya, Stewart-Brown Sarah, Siriwanarangsan Pornthep, Sangrajrang Suleeporn, Shen Hongbing, Chen Kexin, Wu Pei-Ei, Ren Zefang, Haiman Christopher A, Sueta Aiko, Kim Mi Kyung, Khoo Ui Soon, Iwasaki Motoki, Pharoah Paul D P, Wen Wanqing, Hall Per, Shu Xiao-Ou, Easton Douglas F, Kang Daehee
Abstract excerpt
In a consortium including 23 637 breast cancer patients and 25 579 controls of East Asian ancestry, we investigated 70 single-nucleotide polymorphisms (SNPs) in 67 independent breast cancer susceptibility loci recently identified by genome-wide association studies (GWASs) conducted primarily in European-ancestry populations. SNPs in 31 loci showed an association with breast cancer risk at P < 0.05 in a direction...
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