Article
Ability to predict breast cancer in Asian women using a polygenic susceptibility model.
Breast cancer research and treatment - 1 Jun 2011
Hartman Mikael, Suo Chen, Lim Wei Yen, Miao Hui, Teo Yik Ying, Chia Kee Seng
Abstract excerpt
Recently identified susceptibility alleles from Genome-Wide Association Studies (GWAS) for breast cancer provide an option to stratify women for their breast-cancer risk based on these alleles. This may allow greater precision in targeting preventive efforts at genetically high-risk groups. Given the variation in allele frequencies between populations, the utility of such risk-stratification may vary in different...
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