Article
Association of a gain-of-function variant in LGR4 with central obesity.
Obesity (Silver Spring, Md.) - 1 Jan 2017
Zou Yaoyu, Ning Tinglu, Shi Juan, Chen Maopei, Ding Lin, Huang Ya, Kauderer Sophie, Xu Min, Cui Bin, Bi Yufang, Liu Simin, Hong Jie, Liu Ruixin, Ning Guang, Wang Jiqiu
Abstract excerpt
OBJECTIVE: To determine the relationship of the gain-of-function variant A750T in leucine-rich repeat containing G protein-coupled receptor 4 (LGR4) with central obesity and related metabolic phenotypes. METHODS: The LGR4 A750T (c.2248 G > A) variant was detected by Sanger sequencing in a discovery young population and a validation community-based population with obesity from eastern China. Fat indices determined...
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