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Article

Association between common polymorphism near the MC4R gene and obesity risk: a systematic review and meta-analysis.

PloS one - 1 Jan 2012

Xi Bo, Chandak Giriraj R, Shen Yue, Wang Qijuan, Zhou Donghao

Abstract excerpt

BACKGROUND: Genome-wide association studies on Europeans have shown that two polymorphisms (rs17782313, rs12970134) near the melanocortin 4 receptor (MC4R) gene were associated with increased risk of obesity. Subsequently studies among different ethnic populations have shown mixed results with some confirming and others showing inconsistent results, especially among East Asians and Africans. We performed a...

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Identifiers

PMID: 23049848
DOI: 10.1371/journal.pone.0045731
PMCID: PMC3458070

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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