Article
Strong influence of variants near MC4R on adiposity in children and adults: a cross-sectional study in Indian population.
Journal of human genetics - 1 Jan 2013
Dwivedi Om Prakash, Tabassum Rubina, Chauhan Ganesh, Kaur Ismeet, Ghosh Saurabh, Marwaha Raman K, Tandon Nikhil, Bharadwaj Dwaipayan
Abstract excerpt
Common variants near melanocortin 4 receptor (MC4R) gene are shown to be associated with adiposity but have varied effects in different age groups. Among Indians, studies have shown association of these variants with obesity in adults, but their association in children is yet to be confirmed. We evaluated association of rs17782313 and rs12970134 near MC4R with adiposity and related traits in Indians including...
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