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Article

Descriptive analysis of MC4R gene variants associated with obesity listed on ClinVar.

Science progress - 1 Jan 2024

Bayhaghi Giti, Karim Zubair A, Silva Jeane

Abstract excerpt

OBJECTIVES: The most recent version of ClinVar was utilized to filter variants of the MC4R gene based on location, condition, and clinical significance with the goal of obtaining benign and disease-associated variants of the MC4R gene. MC4R gene variants can lead to dysregulation of energy expenditure and appetite control, which prompted this study to delineate the distinctive features of MC4R gene variants...

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Topics

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Share to Databases, Genetic
Share to Genetic Predisposition to Disease
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Obesity

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Share to Receptor, Melanocortin, Type 4

Source

Open in PubMed Open full text

Identifiers

PMID: 39552559
DOI: 10.1177/00368504241297197
PMCID: PMC11571248

Genes

MC4R

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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