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Article

Uncoupling protein 2 deficiency reduces proliferative capacity of murine pancreatic stellate cells.

Hepatobiliary & pancreatic diseases international : HBPD INT - 1 Dec 2016

Muller Sarah, Klingbeil Sandra Maria, Sandica Andreea, Jaster Robert

Abstract excerpt

BACKGROUND: Uncoupling protein 2 (UCP2) has been suggested to inhibit mitochondrial production of reactive oxygen species (ROS) by decreasing the mitochondrial membrane potential. Experimental acute pancreatitis is associated with increased UCP2 expression, whereas UCP2 deficiency retards regeneration of aged mice from acute pancreatitis. Here, we have addressed biological and molecular functions of UCP2 in...

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Source

Identifiers

PMID: 27919855
DOI: 10.1016/s1499-3872(16)60154-6

Genes

UCP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Uncoupling protein 2 deficiency reduces proliferative capacity of murine pancreatic stellate cells.PMID 27919855Read ↗

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