Article
Antifibrogenic effects of vitamin D derivatives on mouse pancreatic stellate cells.
World journal of gastroenterology - 14 Jan 2018
Wallbaum Peter, Rohde Sarah, Ehlers Luise, Lange Falko, Hohn Alexander, Bergner Carina, Schwarzenböck Sarah Marie, Krause Bernd Joachim, Jaster Robert
Abstract excerpt
AIM: To study the molecular effects of three different D-vitamins, vitamin D2, vitamin D3 and calcipotriol, in pancreatic stellate cells (PSCs). METHODS: Quiescent PSCs were isolated from mouse pancreas and activated in vitro by seeding on plastic surfaces. The cells were exposed to D-vitamins as primary cultures (early-activated PSCs) and upon re-culturing (fully-activated cells). Exhibition of vitamin...
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