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Article

Involvement of AP-1 proteins in pancreatic stellate cell activation in vitro.

International journal of colorectal disease - 1 Sept 2004

Fitzner Brit, Sparmann Gisela, Emmrich Jörg, Liebe Stefan, Jaster Robert

Abstract excerpt

BACKGROUND AND AIMS: Pancreatic stellate cells (PSCs) play a key role in the development of pancreatic fibrosis. The molecular mechanisms underlying their activation in response to profibrogenic mediators, however, are largely unknown. Extending previous studies on the transcriptional regulation of PSC activation, we have now focused on the involvement of activator protein (AP)-1. MATERIALS AND METHODS: Using...

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Source

Identifiers

PMID: 14727130
DOI: 10.1007/s00384-003-0565-1

Genes

STAT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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