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Article

Targeted expression of uncoupling protein 2 to mouse liver increases the susceptibility to lipopolysaccharide/galactosamine-induced acute liver injury.

Hepatology (Baltimore, Md.) - 1 Oct 2009

Shang Yingli, Liu Yong, Du Lei, Wang Youliang, Cheng Xuan, Xiao Weiming, Wang Xiaohui, Jin Haijing, Yang Xiao, Liu Shusen, Chen Quan

Abstract excerpt

UNLABELLED: Normal hepatocytes do not express endogenous uncoupling protein 2 (UCP2) in adult liver, although Kupffer cells do, and it is strikingly induced in hepatocytes in steatotic liver and obese conditions. However, the direct link of UCP2 with the pathogenic development of liver diseases a...

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Source

Identifiers

PMID: 19637283
DOI: 10.1002/hep.23121

Genes

UCP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19637283-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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