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Article

A comparison study of multivariate fixed models and Gene Association with Multiple Traits (GAMuT) for next-generation sequencing.

Genetic epidemiology - 1 Jan 2017

Chiu Chi-Yang, Jung Jeesun, Wang Yifan, Weeks Daniel E, Wilson Alexander F, Bailey-Wilson Joan E, Amos Christopher I, Mills James L, Boehnke Michael, Xiong Momiao, Fan Ruzong

Abstract excerpt

In this paper, extensive simulations are performed to compare two statistical methods to analyze multiple correlated quantitative phenotypes: (1) approximate F-distributed tests of multivariate functional linear models (MFLM) and additive models of multivariate analysis of variance (MANOVA), and (2) Gene Association with Multiple Traits (GAMuT) for association testing of high-dimensional genotype data. It is...

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Identifiers

PMID: 27917525
DOI: 10.1002/gepi.22014
PMCID: PMC5154843

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Source receipt: pubmed, retrieved 7 Sept 2026.

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