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Article

An efficient genome-wide association test for multivariate phenotypes based on the Fisher combination function.

BMC bioinformatics - 5 Jan 2016

Yang James J, Li Jia, Williams L Keoki, Buu Anne

Abstract excerpt

BACKGROUND: In genome-wide association studies (GWAS) for complex diseases, the association between a SNP and each phenotype is usually weak. Combining multiple related phenotypic traits can increase the power of gene search and thus is a practically important area that requires methodology work. This study provides a comprehensive review of existing methods for conducting GWAS on complex diseases with multiple...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26729364
DOI: 10.1186/s12859-015-0868-6
PMCID: PMC4704475

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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