Article
Statistical methods for association tests of multiple continuous traits in genome-wide association studies.
Annals of human genetics - 1 Jul 2015
Wu Baolin, Pankow James S
Abstract excerpt
Multiple correlated traits are often collected in genetic studies. The joint analysis of multiple traits could have increased power by aggregating multiple weak effects and offer additional insights into the aetiology of complex human diseases by revealing pleiotropic variants. We propose to study multivariate test statistics to detect single nucleotide polymorphism (SNP) association with multiple correlated...
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