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Article

Age-Dependent Effects of Catechol-O-Methyltransferase (COMT) Gene Val158Met Polymorphism on Language Function in Developing Children.

Cerebral cortex (New York, N.Y. : 1991) - 1 Jan 2017

Sugiura Lisa, Toyota Tomoko, Matsuba-Kurita Hiroko, Iwayama Yoshimi, Mazuka Reiko, Yoshikawa Takeo, Hagiwara Hiroko

Abstract excerpt

The genetic basis controlling language development remains elusive. Previous studies of the catechol-O-methyltransferase (COMT) Val158Met genotype and cognition have focused on prefrontally guided executive functions involving dopamine. However, COMT may further influence posterior cortical regions implicated in language perception. We investigated whether COMT influences language ability and cortical language...

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Source

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Identifiers

PMID: 27909011
DOI: 10.1093/cercor/bhw371
PMCID: PMC6044402

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Age-Dependent Effects of Catechol-O-Methyltransferase (COMT) Gene Val158Met Polymorphism on Language Function in Developing Children.PMID 27909011Read ↗

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