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Article

Effect of the COMT Val158Met genotype on lateral prefrontal activations in young children.

Developmental science - 1 Sept 2018

Moriguchi Yusuke, Shinohara Ikuko

Abstract excerpt

Low executive function (EF) during early childhood is a major risk factor for developmental delay, academic failure, and social withdrawal. Susceptible genes may affect the molecular and biological mechanisms underpinning EF. More specifically, genes associated with the regulation of prefrontal dopamine may modulate the response of prefrontal neurons during executive control. Several studies with adults and older...

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Share to Catechol O-Methyltransferase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

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Source

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Identifiers

PMID: 29314589
DOI: 10.1111/desc.12649
PMCID: PMC6175303

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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