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Article

The catechol-O-methyltransferase gene (COMT) and cognitive function from childhood through adolescence.

Biological psychology - 1 Feb 2013

Gaysina Darya, Xu Man K, Barnett Jennifer H, Croudace Tim J, Wong Andrew, Richards Marcus, Jones Peter B

Abstract excerpt

Genetic variation in the catechol-O-methyltransferase gene (COMT) can influence cognitive function, and this effect may depend on developmental stage. Using a large representative British birth cohort, we investigated the effect of COMT on cognitive function (verbal and non-verbal) at ages 8 and 15 years taking into account the possible modifying effect of pubertal stage. Five functional COMT polymorphisms,...

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Identifiers

PMID: 23178897
DOI: 10.1016/j.biopsycho.2012.11.007
PMCID: PMC3580283

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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