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The COMTp.Val158Met Polymorphism and Cognitive Performance in Adult Development, Healthy Aging and Mild Cognitive Impairment.

Dementia and geriatric cognitive disorders - 1 Jan 2016

Degen Christina, Zschocke Johannes, Toro Pablo, Sattler Christine, Wahl Hans-Werner, Schönknecht Peter, Schröder Johannes

Abstract excerpt

BACKGROUND: The impact of genetic polymorphisms on cognition is assumed to increase with age as losses of brain resources have to be compensated for. We investigate the relation of catechol-O-methyltransferase (COMT)p.Val158Met polymorphism and cognitive capacity in the course of adult development, healthy aging and the development of mild cognitive impairment (MCI) in two birth cohorts of subjects born between...

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Identifiers

PMID: 26489081
DOI: 10.1159/000439585

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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