Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Strong Association of Lipid Metabolism Related MicroRNA Binding Sites Polymorphisms with the Risk of Late Onset Alzheimer's Disease.

Current neurovascular research - 1 Jan 2017

Tan Lin, Xing Ang, Zhao Da-Long, Sun Fu-Rong, Tan Meng-Shan, Wan Yu, Tan Chen-Chen, Zhang Wei, Miao Dan, Yu Jin-Tai, Tan Lan

Abstract excerpt

Although altered lipid metabolism has been extensively implicated in the pathogenesis of late onset Alzheimer's disease (LOAD) through cell biological and epidemiological studies, genetic studies linking lipid metabolism and LOAD are still not well understood. MicroRNAs (miRNAs) exert posttranscriptional down-regulation and their target sequence on the 3' untranslated regions (3'UTR) may be altered by single...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People

Share to Gene Frequency

Share to Genetic Association Studies

Share to Lipid Metabolism

Share to MicroRNAs

Source

Identifiers

PMID: 27897113
DOI: 10.2174/1567202613666161027101100

Genes

CLU
LPL
LRP6
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Strong Association of Lipid Metabolism Related MicroRNA Binding Sites Polymorphisms with the Risk of Late Onset Alzheimer's Disease.PMID 27897113Read ↗

A Genome-Wide Study of Single-Nucleotide Polymorphisms in MicroRNAs and Further In Silico Analysis Reveals Their Putative Role in Susceptibility to Late-Onset Alzheimer's Disease.Semantic proximity Read ↗

The Association of MME microRNA Binding Site Polymorphism with the Risk of Late Onset Alzheimer's Disease in Northern Han Chinese.Semantic proximity Read ↗

Implication of CLU gene polymorphisms in Chinese patients with Alzheimer's disease.Semantic proximity Read ↗

Genetic variation in clusterin gene and Alzheimer's disease risk in Han Chinese.Semantic proximity Read ↗

Altered gene expression in late-onset Alzheimer's disease due to SNPs within 3'UTR microRNA response elements.Semantic proximity Read ↗

Polymorphisms in lipid metabolism related miRNA binding sites and risk of metabolic syndrome.Semantic proximity Read ↗

Validate association of gene loci and establish genetic risk prediction models for late-onset Alzheimer's disease in Chinese populations.Semantic proximity Read ↗

Identification of RNA modification-associated single-nucleotide polymorphisms in genomic loci for low-density lipoprotein cholesterol concentrations.Semantic proximity Read ↗

A systematic analysis highlights multiple long non-coding RNAs associated with cardiometabolic disorders.Semantic proximity Read ↗

The Association Between Clusterin and APOE Polymorphisms and Late-Onset Alzheimer Disease in a Turkish Cohort.Semantic proximity Read ↗

Association between LRP1 C766T polymorphism and Alzheimer's disease susceptibility: a meta-analysis.Semantic proximity Read ↗

Genetic Variants of Lipoprotein Lipase and Regulatory Factors Associated with Alzheimer's Disease Risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.