Article
Identification of RNA modification-associated single-nucleotide polymorphisms in genomic loci for low-density lipoprotein cholesterol concentrations.
Pharmacogenomics - 1 Jul 2022
Tang Fan, Duan Chengcheng, Li Ru, Zhang Huan, Mo Xingbo
Abstract excerpt
Introduction: Genome-wide association studies have identified approximately 1000 lipid-associated loci, but functional variants are less known. Materials & methods: The authors identified RNA modification-related single-nucleotide polymorphisms (RNAm-SNPs) in summary data from a genome-wide association study. By applying Mendelian randomization analysis, the authors identified gene expression levels involved in...
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