Article
Altered gene expression in late-onset Alzheimer's disease due to SNPs within 3'UTR microRNA response elements.
Genomics - 1 Jul 2017
Roy Jyoti, Mallick Bibekanand
Abstract excerpt
Late-onset Alzheimer's disease (LOAD) is a progressive and fatal neurodegenerative disease found in people older than 65years of age. Disease etiology is complex, as susceptibility has been linked to multiple gene variants conferred by single nucleotide polymorphisms (SNPs). However, the molecular mechanisms by which SNPs contribute to LOAD pathogenesis have not been extensively studied, particularly for SNPs...
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