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Article

Validate association of gene loci and establish genetic risk prediction models for late-onset Alzheimer's disease in Chinese populations.

Journal of Alzheimer's disease : JAD - 1 May 2025

Li Fangyu, Zheng Menghan, Jia Jianping

Abstract excerpt

BackgroundMore than 60 independent single-nucleotide polymorphisms (SNPs) have been associated with Alzheimer's disease risk by genome-wide association studies in European.ObjectiveWe aimed to confirm these SNPs in Chinese Han populations and investigate the utility of these genetic markers.MethodsAltogether 1595 late-onset Alzheimer's disease (LOAD) patients and 2474 controls from Chinese population were...

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Identifiers

PMID: 40116671
DOI: 10.1177/13872877251326283

Genes

APOE
MS4A6A
PICALM

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