Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Supt20 is required for development of the axial skeleton.

Developmental biology - 15 Jan 2017

Warrier Sunita, Nuwayhid Samer, Sabatino Julia A, Sugrue Kelsey F, Zohn Irene E

Abstract excerpt

Somitogenesis and subsequent axial skeletal development is regulated by the interaction of pathways that determine the periodicity of somite formation, rostrocaudal somite polarity and segment identity. Here we use a hypomorphic mutant mouse line to demonstrate that Supt20 (Suppressor of Ty20) is required for development of the axial skeleton. Supt20 hypomorphs display fusions of the ribs and vertebrae at lower...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Patterning
Share to Bone Development
Share to Cell Polarity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mesoderm

Share to Neural Crest

Share to Receptors, Notch

Share to Somites

Source

Open in PubMed Open full text

Identifiers

PMID: 27894818
DOI: 10.1016/j.ydbio.2016.11.009
PMCID: PMC5209264

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Supt20 is required for development of the axial skeleton.PMID 27894818Read ↗

Tbx24, encoding a T-box protein, is mutated in the zebrafish somite-segmentation mutant fused somites.Semantic proximity Read ↗

The long and short of it: somite formation in mice.Semantic proximity Read ↗

Targeted Deletion of Btg1 and Btg2 Results in Homeotic Transformation of the Axial Skeleton.Semantic proximity Read ↗

Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton.Semantic proximity Read ↗

Proper Gcn5 histone acetyltransferase expression is required for normal anteroposterior patterning of the mouse skeleton.Semantic proximity Read ↗

Defective somite patterning in mouse embryos with reduced levels of Tbx6.Semantic proximity Read ↗

The role of the SPT6 chromatin remodeling factor in zebrafish embryogenesis.Semantic proximity Read ↗

Differential axial requirements for lunatic fringe and Hes7 transcription during mouse somitogenesis.Semantic proximity Read ↗

The mouse rib-vertebrae mutation disrupts anterior-posterior somite patterning and genetically interacts with a Delta1 null allele.Semantic proximity Read ↗

Ripply2 is essential for precise somite formation during mouse early development.Semantic proximity Read ↗

Tgif1 and Tgif2 Regulate Axial Patterning in Mouse.Semantic proximity Read ↗

Mutation of a ubiquitously expressed mouse transmembrane protein (Tapt1) causes specific skeletal homeotic transformations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.