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Article

The role of the SPT6 chromatin remodeling factor in zebrafish embryogenesis.

Developmental biology - 15 Jul 2007

Kok Fatma O, Oster Emma, Mentzer Laura, Hsieh Jen-Chih, Henry Clarissa A, Sirotkin Howard I

Abstract excerpt

Somitogenesis is a highly controlled process that results in segmentation of the paraxial mesoderm. Notch pathway activity in the presomitic mesoderm is fundamental for management of synchronized gene expression which is necessary for regulation of somitogenesis. We have isolated an embryonic lethal mutation, SBU2, that causes somite formation defects very similar to Notch pathway mutants. SBU2 mutants generate...

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Share to Chromatin Assembly and Disassembly
Share to Epistasis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to In Situ Hybridization

Share to Receptors, Notch

Share to Somites

Share to Zebrafish

Share to Zebrafish Proteins

Source

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Identifiers

PMID: 17570355
DOI: 10.1016/j.ydbio.2007.04.039
PMCID: PMC2049011

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