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Article

Ripply2 is essential for precise somite formation during mouse early development.

FEBS letters - 12 Jun 2007

Chan Techuan, Kondow Akiko, Hosoya Akihiro, Hitachi Keisuke, Yukita Akira, Okabayashi Koji, Nakamura Hiroaki, Ozawa Hidehiro, Kiyonari Hiroshi, Michiue Tatsuo, Ito Yuzuru, Asashima Makoto

Abstract excerpt

The regions of expression of Ripply1 and Ripply2, presumptive transcriptional corepressors, overlap at the presomitic mesoderm during somitogenesis in mouse and zebrafish. Ripply1 is required for somite segmentation in zebrafish, but the developmental role of Ripply2 remains unclear in both species. Here, we generated Ripply2 knock-out mice to investigate the role of Ripply2. Defects in segmentation of the axial...

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Identifiers

PMID: 17531978
DOI: 10.1016/j.febslet.2007.05.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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