Article
The long and short of it: somite formation in mice.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Sept 2006
Gridley Thomas
Abstract excerpt
A fundamental characteristic of the vertebrate body plan is its segmentation along the anterior-posterior axis. This segmental pattern is established during embryogenesis by the formation of somites, the transient epithelial blocks of cells that derive from the unsegmented presomitic mesoderm. Somite formation involves a molecular oscillator, termed the segmentation clock, in combination with gradients of...
Topics
- Animals
- Biological Clocks
- Body Patterning
- Female
- Gene Expression Regulation, Developmental
- Genes, Homeobox
- Humans
- Mesoderm
- Mice
- Mutation
- Pregnancy
- Receptors, Notch
- Signal Transduction
- Somites
- Spine