Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Severe changes in colon epithelium in the Mecp2-null mouse model of Rett syndrome

16 Nov 2016

Abstract excerpt

BACKGROUND: Rett syndrome is best known due to its severe and devastating symptoms in the central nervous system. It is produced by mutations affecting the Mecp2 gene that codes for a transcription factor. Nevertheless, evidence for MECP2 activity has been reported for tissues other than those of the central nervous system. Patients affected by Rett presented with intestinal affections whose origin is still not...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child Nutrition and Feeding Issues
Share to Endoplasmic Reticulum Stress and Disease
Share to Genetics and Neurodevelopmental Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27868160
DOI: 10.1186/s40348-016-0065-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Severe changes in colon epithelium in the Mecp2-null mouse model of Rett syndromePMID 27868160Read ↗

Genetic Mouse Models with Intestinal-Specific Tight Junction Deletion Resemble an Ulcerative Colitis Phenotype.Semantic proximity Read ↗

Expression level of Hand2 affects specification of enteric neurons and gastrointestinal function in mice.Semantic proximity Read ↗

Mutation of EpCAM leads to intestinal barrier and ion transport dysfunction.Semantic proximity Read ↗

Morphological and Functional Colonic Defects Caused by a Mutated Thyroid Hormone Receptor α.Semantic proximity Read ↗

Loss of enteric BDNF–TrkB signaling and VIPergic dysfunction underlie gastrointestinal dysmotility in a <i>Mecp2-null</i> mouse model of Rett syndromeSemantic proximity Read ↗

Keratins modulate colonocyte electrolyte transport via protein mistargeting.Semantic proximity Read ↗

Phenotypic Analysis of Mice with Conditional Knockout of PPP2CA in Colonic Tissues.Semantic proximity Read ↗

Functional consequences of EpCam mutation in mice and men.Semantic proximity Read ↗

Colonic epithelial functional phenotype varies with type and phase of experimental colitis.Semantic proximity Read ↗

Deficiency of Protein Tyrosine Phosphatase Non-Receptor Type 2 in Intestinal Epithelial Cells Has No Appreciable Impact on Dextran Sulphate Sodium Colitis Severity But Promotes Wound Healing.Semantic proximity Read ↗

The phenotype of necrotizing enterocolitis correlates with distinct changes of intestinal junctional proteins.Semantic proximity Read ↗

Mucin-2 knockout is a model of intercellular junction defects, mitochondrial damage and ATP depletion in the intestinal epitheliumSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.