Article
Colonic epithelial functional phenotype varies with type and phase of experimental colitis.
Gastroenterology - 1 Jul 2003
Mizoguchi Emiko, Xavier Ramnik J, Reinecker Hans-Christian, Uchino Hirofumi, Bhan Atul K, Podolsky Daniel K, Mizoguchi Atsushi
Abstract excerpt
BACKGROUND & AIMS: Colonic crypt elongation occurs during both chronic colitis and in the recovery phase of acute colitis. The impact of these alterations on epithelial cell functions is not fully defined. METHODS: DNA microarray analysis of freshly isolated colonic epithelial cells (CECs) from acute and chronic colitis was performed, and the results were confirmed by reverse transcription polymerase chain...
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