Article
Animal models of airway diseases.
Sub-cellular biochemistry - 1 Jan 2011
Thompson Linda F, Picher Maryse, Blackburn Michael R
Abstract excerpt
Over the past 20 years, the growing awareness that purinergic signaling events literally shape the immune and inflammatory responses to infection and allergic reactions warranted the development of animal models to assess their importance in vivo in acute lung injury and chronic airway diseases. The pioneer work conducted with the adenosine deaminase (ADA)-deficient mouse provided irrefutable evidence that excess...
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