Article

The novel TRPA1 antagonist BI01305834 inhibits ovalbumin-induced bronchoconstriction in guinea pigs

2021-01-26

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Asthma is a chronic respiratory disease in which the nervous system plays a central role. Sensory nerve activation, amongst others via Transient Receptor Potential Ankyrin 1 (TRPA1) channels, contributes to asthma characteristics including cough, bronchoconstriction, mucus secretion, airway hyperresponsiveness (AHR) and inflammation. In the current study, we eva...

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Literature Corpus work: 92e2794b-7527-5b19-bfff-6ec6af994ffb
DOI: 10.21203/rs.3.rs-88800/v2

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