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Article

[Advance in the research on P2X7 and inflammatory respiratory diseases].

Yao xue xue bao = Acta pharmaceutica Sinica - 1 Aug 2013

Cao Shu-Hua, Yuan Shao-Peng, Hou Qi

Abstract excerpt

P2X7 is the most important subtype of the ATP receptors known so far. Recent investigations showed that the downstream signaling pathway of P2X7 is coupled with several key inflammatory molecules including IL-1beta and IL-18, this suggests P2X7 might have roles in the inflammatory diseases. Moreover, attenuation of P2X7 by selective antagonists in vitro and knockout mice in vivo reducing the inflammatory response...

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Identifiers

PMID: 24187823

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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