The role of the neutrophil receptor Mrgpra2 in the formation of itch in atopic dermatitis

Abstract excerpt

<h4>ABSTRACT</h4> Atopic dermatitis (AD), or eczema, is estimated to affect more than 30 million people in the United States, with over 6 million have moderate or severe disease. Chronic pruritus is a common symptom and is one of most difficult to manage. Even though itch is a major component in the pathology of AD, the biological underpinnings are not fully understood. In the present manuscript we identify a rol...

Topics

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• Anti-Infective Agents
• Mast Cells
• Mutation, Missense
• Nerve Tissue Proteins
• Receptors, G-Protein-Coupled
• Receptors, Neuropeptide
• Skin
• Skin Diseases

Identifiers and source

Literature Corpus work

56740d89-978a-53d3-b981-513f982b5d95

DOI

10.64898/2026.06.12.731726