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Article

A childhood acute lymphoblastic leukemia genome-wide association study identifies novel sex-specific risk variants.

Medicine - 1 Nov 2016

Singh Sandeep K, Lupo Philip J, Scheurer Michael E, Saxena Anshul, Kennedy Amy E, Ibrahimou Boubakari, Barbieri Manuel Alejandro, Mills Ken I, McCauley Jacob L, Okcu Mehmet Fatih, Dorak Mehmet Tevfik

Abstract excerpt

Childhood acute lymphoblastic leukemia (ALL) occurs more frequently in males. Reasons behind sex differences in childhood ALL risk are unknown. In the present genome-wide association study (GWAS), we explored the genetic basis of sex differences by comparing genotype frequencies between male and female cases in a case-only study to assess effect-modification by sex.The case-only design included 236 incident cases...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27861356
DOI: 10.1097/MD.0000000000005300
PMCID: PMC5120913

Genes

RASSF2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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