Article
Impact of the X Chromosome and sex on regulatory variation.
Genome research - 1 Jun 2016
Kukurba Kimberly R, Parsana Princy, Balliu Brunilda, Smith Kevin S, Zappala Zachary, Knowles David A, Favé Marie-Julie, Davis Joe R, Li Xin, Zhu Xiaowei, Potash James B, Weissman Myrna M, Shi Jianxin, Kundaje Anshul, Levinson Douglas F, Awadalla Philip, Mostafavi Sara, Battle Alexis, Montgomery Stephen B
Abstract excerpt
The X Chromosome, with its unique mode of inheritance, contributes to differences between the sexes at a molecular level, including sex-specific gene expression and sex-specific impact of genetic variation. Improving our understanding of these differences offers to elucidate the molecular mechanisms underlying sex-specific traits and diseases. However, to date, most studies have either ignored the X Chromosome or...
Topics
Join the communities discussing this publication.